Revaprazan

Names

[ CAS No. ]:
199463-33-7

[ Name ]:
Revaprazan

[Synonym ]:
Revaprazan [INN]

Biological Activity

[Description]:

Revaprazan (SB 641257) is a reversible proton pump inhibitor with significant anti-inflammatory effects. Revaprazan can be used for chronic gastric inflammation research[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump

[References]

[1]. Li W, et al. Preparation and in vitro/in vivo evaluation of revaprazan hydrochloride nanosuspension. Int J Pharm. 2011 Apr 15;408(1-2):157-62.

[2]. Lee JS, et al. Revaprazan, a novel acid pump antagonist, exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₃FN₄

[ Molecular Weight ]:
362.44300

[ Exact Mass ]:
362.19100

[ PSA ]:
41.05000

[ LogP ]:
5.23780

Revaprazan

Names

Biological Activity

Chemical & Physical Properties

Related Compounds