L-Leucine-2-13C

Names

[ CAS No. ]:
201612-66-0

[ Name ]:
L-Leucine-2-13C

[Synonym ]:
MFCD00144627

Biological Activity

[Description]:

L-Leucine-2-13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

[Related Catalog]:

Signaling Pathways >> PI3K/Akt/mTOR >> mTOR

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Melting Point ]:
>300ºC(lit.)

[ Molecular Formula ]:
C₅₁₃CH₁₃NO₂

[ Molecular Weight ]:
132.16600

[ Exact Mass ]:
132.09800

[ PSA ]:
63.32000

[ LogP ]:
1.14470

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3