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Dasycarpol

Names

[ CAS No. ]:
202343-57-5

[ Name ]:
Dasycarpol

[Synonym ]:
(3R,3aR,6S)-3-(furan-3-yl)-6-hydroxy-3a,7-dimethyl-3a,4,5,6-tetrahydro-2-benzofuran-1(3H)-one
1(3H)-Isobenzofuranone, 3-(3-furanyl)-3a,4,5,6-tetrahydro-6-hydroxy-3a,7-dimethyl-, (3R,3aR,6S)-
(3R,3aR,6S)-3-(3-Furyl)-6-hydroxy-3a,7-dimethyl-3a,4,5,6-tetrahydro-2-benzofuran-1(3H)-one

Biological Activity

[Description]:

Dasycarpol (compound 2) is a product of microbial transformation of fraxinellone by Aspergillus niger (AS 3.421). Dasycarpol shows moderate cytotoxicity against A549 cells ,with the IC50 of 20 ug/mL[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

20 ug/mL in A549 cells[1]


[References]

[1]. Yang RL, Jia TL, Zhang RQ. Microbial transformation of fraxinellone by Aspergillus niger. J Asian Nat Prod Res. 2005;7(6):843-845.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
430.8±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H16O4

[ Molecular Weight ]:
248.27

[ Flash Point ]:
214.3±28.7 °C

[ Exact Mass ]:
248.104858

[ PSA ]:
59.67000

[ LogP ]:
1.23

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.576

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds