NF 340

Names

[ CAS No. ]:
202982-98-7

[ Name ]:
NF 340

[Synonym ]:
2,6-Naphthalenedisulfonic acid, 4,4'-[carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]]bis-, sodium salt (1:4)
Tetrasodium 4,4'-{carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]}di(2,6-naphthalenedisulfonate)

Biological Activity

[Description]:

NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> P2Y Receptor

Research Areas >> Inflammation/Immunology

[Target]

P2Y11 receptor[1]

[References]

[1]. Feng Gao, et al. P2Y11 receptor antagonist NF340 ameliorates inflammation in human fibroblast-like synoviocytes: An implication in rheumatoid arthritis. IUBMB Life. 2019 Oct;71(10):1552-1560.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₇H₂₆N₄Na₄O₁₅S₄

[ Molecular Weight ]:
986.84

[ Exact Mass ]:
985.986816

NF 340

Names

Biological Activity

Chemical & Physical Properties

Related Compounds