Mal-PEG2-Val-Cit-amido-PAB-OH

Names

[ CAS No. ]:
2055041-38-6

[ Name ]:
Mal-PEG2-Val-Cit-amido-PAB-OH

Biological Activity

[Description]:

Mal-PEG2-Val-Cit-amido-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₄₂N₆O₉

[ Molecular Weight ]:
618.68

Safety Information

[ Hazard Codes ]:
Xi

Mal-PEG2-Val-Cit-amido-PAB-OH

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds