Calcium trinatrium diethylenetriaminepentaacetic acid hydrate

Names

[ CAS No. ]:
207226-35-5

[ Name ]:
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate

[Synonym ]:
MFCD00150947

Biological Activity

[Description]:

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic inhibitor of CMV replication[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> CMV

[In Vitro]

The antiviral activity of Calcium trinatrium diethylenetriaminepentaacetic acid hydrate is suppressed by metal ions with a decreasing potency order of Mn2+/Zn2+>Fe2+>Cu2+>Fe3+. Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate inhibits CMV L-antigen production with EC50 ranging from 6.1 to 9.9 μM[2].

[References]

[1]. Eybl V, et al. Effect of cadmium chelating agents on organ cadmium and trace element levels in mice. Analyst. 1998;123(1):25-26.

[2]. Cinatl J Jr, et al. In vitro inhibition of human cytomegalovirus replication by calcium trinatrium diethylenetriaminepentaacetic acid. Antiviral Res. 1996;31(1-2):23-34.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₂₀CaN₃Na₃O₁₁

[ Molecular Weight ]:
515.36900

[ Exact Mass ]:
515.04200

[ PSA ]:
219.60000