N-Benzoylglycyl-L-histidyl-L-leucine hydrate

Names

[ CAS No. ]:
207386-83-2

[ Name ]:
N-Benzoylglycyl-L-histidyl-L-leucine hydrate

[Synonym ]:
N-Benzoylglycyl-L-histidyl-L-leucine hydrate (1:1)
N-Benzoylglycyl-L-histidyl-L-leucine hydrate
L-Leucine, N-benzoylglycyl-L-histidyl-, hydrate (1:1)
N-Hippuryl-L-histidyl-L-leucine hydrate
N-Benzoyl-Gly-His-Leu hydrate
N-Hippuryl-His-Leu hydrate
N-Benzoyl-Gly-His-Leu
Bz-Gly-His-Ile-OH
MFCD00149318
EINECS 250-597-9

Biological Activity

[Description]:

N-Benzoyl-Gly-His-Leu hydrate is a leucine derivative, a polypeptide. N-Benzoyl-Gly-His-Leu hydrate exerts function with angiotensin converting enzyme (ACE) substrate.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Melting Point ]:
108-110ºC (dec.)

[ Molecular Formula ]:
C₂₁H₂₉N₅O₆

[ Molecular Weight ]:
447.485

[ Exact Mass ]:
447.211792

[ PSA ]:
162.51000

[ LogP ]:
1.59090

[ Appearance of Characters ]:
white to off-white

[ Storage condition ]:
−20°C

[ Water Solubility ]:
acetic acid: ~50mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Alteration of Gene Expression Profile in Kidney of Spontaneously Hypertensive Rats Treated with Protein Hydrolysate of Blue Mussel (Mytilus edulis) by DNA Microarray Analysis.

PLoS ONE 10(10) , e0142016, (2015)

Marine organisms are rich sources of bioactive components, which are often reported to have antihypertensive effects. However, the underlying mechanisms have yet to be fully identified. The aim of thi...

Angiotensin I-converting enzyme inhibitor activity on egg albumen fermentation.

Asian. Australas. J. Anim. Sci. 28(6) , 855-61, (2015)

Lactobacillus plantarum is used for fermentation of fish products, meat and milk. However, the utilization of these bacteria in egg processing has not been done. This study was designed to evaluate th...

Prolonged atrial natriuretic peptide exposure stimulates guanylyl cyclase-a degradation.

Endocrinology 151 , 2769-76, (2010)

Natriuretic peptide receptor-A (NPR-A), also known as guanylyl cyclase-A, is a transmembrane receptor guanylyl cyclase that is activated by the cardiac hormones atrial natriuretic peptide and B-type n...