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F 14679

Names

[ CAS No. ]:
208109-38-0

[ Name ]:
F 14679

Biological Activity

[Description]:

F 14679 is a prototypical 5-HT1A agonist with a pKi of 10.23. F 14679 induces large Ca2+ responses[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

5-HT1A Receptor:10.23 (pKi)

5-HT1B Receptor:5.12 (pIC50)

[References]

[1]. Pauwels PJ, et al. Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₅ClF₂N₄O

[ Molecular Weight ]:
422.90

Related Compounds