Lipid M

Names

[ CAS No. ]:
2089251-57-8

[ Name ]:
Lipid M

Biological Activity

[Description]:

Lipid M (pKa: 6.75) can be used to deliver mRNA vaccine and yield a robust immune response with improved tolerability[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vivo]

Lipid M (50 μL containing 2 μg of luciferase mRNA formulated in LNPs, i.m.) is followed by rapid clearance in muscle, spleen and liver in CD-1 mice[1]. Lipid M (300 μL containing 500 μg IgG mRNA formulated in LNPs, i.m.) yields serum antibody expression comparable to that of MC3-based LNPs in cynomolgus monkeys[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C44H87NO5

[ Molecular Weight ]:
710.17

Related Compounds