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Budigalimab

Names

[ CAS No. ]:
2098225-93-3

[ Name ]:
Budigalimab

Biological Activity

[Description]:

Budigalimab (ABBV 181; PR 1648817) is a humanized IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. Budigalimab is Fc mutated thus to reduce Fc receptor interactions and limit effector function[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1

[Target]

programmed cell death 1 (PD-1) receptor[1]


[References]

[1]. Powderly J, et al. Model Informed Dosing Regimen and Phase I Results of the Anti-PD-1 Antibody Budigalimab (ABBV-181). Clin Transl Sci. 2021 Jan;14(1):277-287.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds