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(Rac)-BAY-985

Names

[ CAS No. ]:
2101925-20-4

[ Name ]:
(Rac)-BAY-985

Biological Activity

[Description]:

(Rac)-BAY-985 (Compound Example 100.01) is a potent, ATP-competitive and selective TBK1 inhibitor with an IC50 of 1.5 nM. Antitumor efficacy[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> IKK
Research Areas >> Cancer

[Target]

TBK1:1.5 nM (IC50)


[References]

[1]. Volker Schulze, et al. Heteroarylbenzimidazole compounds. WO2017102091A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H30F3N9O

[ Molecular Weight ]:
553.58


Related Compounds