Gallein

Names

[ Name ]:
Gallein

[Synonym ]:
MORDANT VIOLET 25
Alizarin violet
ANTHRACENE VIOLET
ALIZARIN VIOLET
(4,5,6-trihydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
4',5'-dihydroxyfluorescein
GALLIEN
3',4',5',6'-tetrahydroxy-spiro[phthalan-1,9'-xanthen]-3-one
Alizarinvio-letGBS
3',4',5',6'-tetrahydroxyspiro(isobenzofuran-1(3H),9'-[9H]xanthene)-3-one
SM-21 maleate
3',4',5',6'-Tetrahydroxy-spiro[phthalan-1,9'-xanthen]-3-on
Callein
Mordant Violet 25
pyrogallophthalein
3',4',5',6'-Tetrahydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
EINECS 218-272-6

Biological Activity

[Description]:

Gallein is a G protein βγ (Gβγ) subunit signalling inhibitor. Gallein disrupts the interaction of Gβγ subunits with the PI3Kγ. Anticancer agent[1]. Gallein used as a red dye, an acid-base indicator and as a detection reagent for phosphates[2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Sanz G, et al. Gallein, a Gβγ subunit signalling inhibitor, inhibits metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand. BMC Res Notes. 2017 Oct 30;10(1):541.

[2]. Lillie RD, et al. Hematoxylin substitutes: gallein as a biological stain. Stain Technol. 1974 Nov;49(6):339-46.

Chemical & Physical Properties

[ Density]:
1.81g/cm3

[ Boiling Point ]:
687.4ºC at 760mmHg

[ Melting Point ]:
>300°C

[ Molecular Formula ]:
C₂₀H₁₂O₇

[ Molecular Weight ]:
364.30500

[ Flash Point ]:
255.2ºC

[ Exact Mass ]:
364.05800

[ PSA ]:
116.45000

[ LogP ]:
3.07700

[ Vapour Pressure ]:
1.57E-19mmHg at 25°C

[ Index of Refraction ]:
1.865

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Solubility Almost insoluble in water, benzene, chloroform; soluble in ethanol, acetone

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2932999099

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%