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6β-Acetoxy-15,23-dideoxy-19,23-epoxyajaconine

Names

[ CAS No. ]:
21040-64-2

[ Name ]:
6β-Acetoxy-15,23-dideoxy-19,23-epoxyajaconine

[Synonym ]:
spiradine-F
(1S,2R,5S,7R,8R,12R,18R,20S,21R)-12-Methyl-4-methylene-14,19-dioxa-17-azaheptacyclo[10.7.2.2.0.0.0.0]tricos-20-yl acetate
Renormax
Spirapril hydrochloride
Spirapril HCl
spiprapril hydrochloride

Biological Activity

[Description]:

Spiradine F is a main alkaloidal component of spiraea japonioa L. fil. Spiradine F derivative can inhibit platelet-activating factor (PAF)-induced platelet aggregation[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Others >> Others

[References]

[1]. Masaaki Toda, et al. The structures of spiradines F and G from spiraea japonioa L. fil. Tetrahedron Letters. Volume 9, Issue 53, 1968. 5565-5568.

[2]. Ling Li, et al. Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica. European Journal of Pharmacology. Volume 449, Issues 1-2. 2002. 23-28.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
510.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H33NO4

[ Molecular Weight ]:
399.52

[ Flash Point ]:
262.5±30.1 °C

[ Exact Mass ]:
399.240967

[ PSA ]:
48.00000

[ LogP ]:
4.24

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.603

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds