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BET-IN-2

Names

[ CAS No. ]:
2104688-91-5

[ Name ]:
BET-IN-2

Biological Activity

[Description]:

BET-IN-2 is a BET inhibitor with an IC50 of 52 nM for BRD4-BD1.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

[Target]

BRD4 BD1:52 nM (IC50)

[References]

[1]. Hu J, et al. Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor. Eur J Med Chem. 2017 Sep 8;137:176-195.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₉N₃O

[ Molecular Weight ]:
363.50

Related Compounds