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koenimbine

Names

[ CAS No. ]:
21087-98-9

[ Name ]:
koenimbine

[Synonym ]:
Koenimbin
Koenimbine
O-methyl mukonal

Biological Activity

[Description]:

Koenimbine is an anticancer agent that can be obtained from the leaves and fruits of Murraya koenigii. Koenimbine can induce apoptosis and necrosis in HT-29 and SW48 cells. Koenimbine can be used in the research of cancer[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Astaneh M, et al. Assessment of anti-cancer effects of koenimbine on colon cancer cells. Hum Antibodies. 2020;28(3):185-190.  

Chemical & Physical Properties

[ Density]:
1.193g/cm3

[ Boiling Point ]:
482.1ºC at 760 mmHg

[ Melting Point ]:
194-195℃

[ Molecular Formula ]:
C19H19NO2

[ Molecular Weight ]:
293.36

[ Flash Point ]:
171.8ºC

[ Exact Mass ]:
293.14200

[ PSA ]:
34.25000

[ LogP ]:
4.82230

[ Vapour Pressure ]:
5.5E-09mmHg at 25°C

[ Index of Refraction ]:
1.658

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H413

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36-53

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds