Rubranol

Names

[ Name ]:
Rubranol

[Synonym ]:
1,2-Benzenediol, 4-[(3R)-7-(3,4-dihydroxyphenyl)-3-hydroxyheptyl]-
4-[(3R)-7-(3,4-Dihydroxyphenyl)-3-hydroxyheptyl]-1,2-benzenediol
(R)-1,7-Bis-(3,4-dihydroxyphenyl)-5-hydroxyheptane

Biological Activity

[Description]:

Rubranol is an inhibitor of NO Synthase. Rubranol inhibits LPS-induced NO production in activated macrophages with 74% inhibition[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

Research Areas >> Inflammation/Immunology

[References]

[1]. Lai YC, et al. A comprehensive investigation of anti-inflammatory diarylheptanoids from the leaves of Alnus formosana. Phytochemistry. 2012 Jan;73(1):84-94.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
611.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₂₄O₅

[ Molecular Weight ]:
332.391

[ Flash Point ]:
286.1±26.1 °C

[ Exact Mass ]:
332.162384

[ PSA ]:
101.15000

[ LogP ]:
2.54

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.639

Safety Information

[ Hazard Codes ]:
Xi