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Biotin-XX hydrazide

Names

[ CAS No. ]:
211237-33-1

[ Name ]:
Biotin-XX hydrazide

[Synonym ]:
Hexanoic acid, 6-[[6-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-1-oxohexyl]amino]-, hydrazide
N-(6-Hydrazino-6-oxohexyl)-6-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanamide
Biotin-XX hydrazide

Biological Activity

[Description]:

Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Biotin-XX hydrazide contains two aminohexanoic acid spacers which greatly enhances the efficiency of formation of the complex between the biotinylated antibody (or other biotinylated protein) and the avidin–probe conjugate, where the probe can be a fluorochrome or an enzyme[1].

[References]

[1]. Haugland RP, et, al. Coupling of antibodies with biotin. Methods Mol Biol. 2008;418:13-24.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
904.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H40N6O4S

[ Molecular Weight ]:
484.656

[ Flash Point ]:
501.0±34.3 °C

[ Exact Mass ]:
484.283173

[ PSA ]:
179.75000

[ LogP ]:
-1.66

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.532

Related Compounds