FlAsH-EDT2

Names

[ Name ]:
FlAsH-EDT2

[Synonym ]:
flash-edt2

Biological Activity

[Description]:

FlAsH-EDT2 is a protein labeling reagent. FlAsH-EDT2 also is a membrane-permeant fluorogenic biarsenicals. FlAsH-EDT2 binds to CCXXCC motifs and non-specifically to endogenous cysteine-rich proteins. FlAsH-EDT2 can be useful only for labeling those recombinant proteins that express at a very high level[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Stroffekova K, et al. The protein-labeling reagent FLASH-EDT2 binds not only to CCXXCC motifs but also non-specifically to endogenous cysteine-rich proteins. Pflugers Arch. 2001 Sep;442(6):859-66.

[2]. Adams SR, et al. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008;3(9):1527-34.

Chemical & Physical Properties

[ Boiling Point ]:
849.8ºC at 760 mmHg

[ Molecular Formula ]:
C₂₄H₁₈As₂O₅S₄

[ Molecular Weight ]:
664.50000

[ Flash Point ]:
467.8ºC

[ Exact Mass ]:
663.84700

[ PSA ]:
177.19000

[ LogP ]:
4.01620

[ Vapour Pressure ]:
1.02E-30mmHg at 25°C

FlAsH-EDT2

Names

Biological Activity

Chemical & Physical Properties

Related Compounds