W36017

Names

[ CAS No. ]:
21236-54-4

[ Name ]:
W36017

[Synonym ]:
2-dimethylamino-2',6'-acetoxylidide

Biological Activity

[Description]:

W3601 is the impurity of Lidocaine. W3601 exhibits nerve blocking activity with the pKa of 7.4[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. J A Wildsmith, et al. Differential nerve blockade: esters v. amides and the influence of pKa. Br J Anaesth. 1987 Mar;59(3):379-84.

Chemical & Physical Properties

[ Density]:
1.056g/cm3

[ Boiling Point ]:
320.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₈N₂O

[ Molecular Weight ]:
206.28400

[ Flash Point ]:
147.5ºC

[ Exact Mass ]:
206.14200

[ PSA ]:
35.83000

[ LogP ]:
2.45300

[ Vapour Pressure ]:
0.000321mmHg at 25°C

[ Index of Refraction ]:
1.56

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%