Anti-inflammatory agent 20

Names

[ CAS No. ]:
2127403-65-8

[ Name ]:
Anti-inflammatory agent 20

Biological Activity

[Description]:

Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> COX

[Target]

NF-κB

COX-2

TNF-α


[References]

[1]. Yang G, et al. Design, synthesis and anti-inflammatory activity of 3-amino acid derivatives of ocotillol-type sapogenins. Eur J Med Chem. 2020 Sep 15;202:112507.

Chemical & Physical Properties

[ Molecular Formula ]:
C39H66N2O8

[ Molecular Weight ]:
690.95

Related Compounds