Reuterin

Names

[ Name ]:
Reuterin

[Synonym ]:
Propanal, 3-hydroxy-
β-Hydroxypropionaldehyde
3-Oxo-1-propanol
3-Hydroxypropanal
β-Hydroxypropanal
b-Hydroxypropanal
Reuterin
b-Hydroxypropionaldehyde

Biological Activity

[Description]:

Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Reuterin is water soluble, effective in a wide range of pH, resistant to proteolytic and lipolytic enzymes and has been therefore studied as a food preservative or auxiliary therapeutic agent. Reuterin is a potent antimicrobial with high activity against a broad panel of C. jejuni and C. coli isolates[1]. Reuterin is produced by certain strains of L. reuteri during anaerobic fermentation of glycerol and has a broad-spectrum antimicrobial property against enteric pathogens and intestinal bacteria[2].

[References]

[1]. Schaefer L, et al. The antimicrobial compound reuterin (3-hydroxypropionaldehyde) induces oxidative stress via interaction with thiol groups. Microbiology (Reading). 2010;156(Pt 6):1589-1599.

[2]. Asare PT, et al. Reuterin Demonstrates Potent Antimicrobial Activity Against a Broad Panel of Human and Poultry Meat Campylobacter spp. Isolates. Microorganisms. 2020;8(1):78. Published 2020 Jan 6.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
168.2±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃H₆O₂

[ Molecular Weight ]:
74.078

[ Flash Point ]:
61.8±15.2 °C

[ Exact Mass ]:
74.036781

[ PSA ]:
37.30000

[ LogP ]:
-1.11

[ Vapour Pressure ]:
0.5±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.400

[ Storage condition ]:
-20℃

Safety Information

[ HS Code ]:
2912491000

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2912491000

[ Summary ]:
2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%