STING agonist-1(compound 3)trihydrochloride

diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist.

Signaling Pathways >> Immunology/Inflammation >> STING

Research Areas >> Inflammation/Immunology

STING[1].

diABZI STING agonist-1 (trihydrochloride) activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting−/− mice, confirming that diABZI STING agonist-1 (trihydrochloride) STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.

CCCP | ADU-S100 ammonium salt | DMXAA (Vadimezan) | G10, STING signaling activator | C 176 | Cyclic-di-GMP | cGAMP | diABZI STING agonist-1 (Tautomerism)