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(S,R,S)-AHPC-C4-NH2

Names

[ CAS No. ]:
2138439-53-7

[ Name ]:
(S,R,S)-AHPC-C4-NH2

Biological Activity

[Description]:

(S,R,S)-AHPC-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

VHL


[References]

[1]. Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H39N5O4S

[ Molecular Weight ]:
529.69

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds