Thalidomide-NH-PEG3-propionic acid

Names

[ Name ]:
Thalidomide-NH-PEG3-propionic acid

Biological Activity

[Description]:

Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

Cereblon

[References]

[1]. David Remillard, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.2017 May 15;56(21):5738-5743.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₇N₃O₉

[ Molecular Weight ]:
477.46

Thalidomide-NH-PEG3-propionic acid

Names

Biological Activity

Chemical & Physical Properties

Related Compounds