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GSK3004774

Names

[ CAS No. ]:
2138814-32-9

[ Name ]:
GSK3004774

Biological Activity

[Description]:

GSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> GPCR/G Protein >> CaSR

[References]

[1]. Sparks SM, et al. Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4673-4677.

Chemical & Physical Properties

[ Molecular Formula ]:
C32H40N4O3

[ Molecular Weight ]:
528.69

Related Compounds