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ABBV-744

Names

[ CAS No. ]:
2138861-99-9

[ Name ]:
ABBV-744

Biological Activity

[Description]:

ABBV-744 is a highly BDII-selective BET bromodomain inhibitor, used in the research of inflammatory diseases, cancer, and AIDS.

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Research Areas >> Cancer
Research Areas >> Infection
Research Areas >> Inflammation/Immunology

[Target]

BET bromodomain[1]


[In Vitro]

ABBV-744 is a highly BDII-selective BET bromodomain inhibitor, used in the research of inflammatory diseases, cancer, and AIDS[1].

[References]

[1]. FIDANZE, Steven D., et al. BROMODOMAIN INHIBITORS. WO 2017177955 A1.


[Related Small Molecules]

(+)-JQ1 | GSK126 | Tazemetostat (EPZ-6438) | Birabresib (OTX015) | A 485 | Curcumin | ARV-771 | ARV-825 | I-BET762 | BI 2536 | GSK343 | C646 | 3-Deazaneplanocin A (hydrochloride) | I-BET151 | 666-15

Chemical & Physical Properties

[ Molecular Formula ]:
C28H30FN3O4

[ Molecular Weight ]:
491.55

[ Storage condition ]:
-20℃

Related Compounds