Pomalidomide 4'-PEG5-acid
Names
[ CAS No. ]:
2139348-63-1
[ Name ]:
Pomalidomide 4'-PEG5-acid
Biological Activity
[Description]:
Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology[1].
[Related Catalog]:
[Target]
Cereblon
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C26H35N3O11
[ Molecular Weight ]:
565.57
[ Storage condition ]:
-20°C