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MDH1-IN-2

Names

[ CAS No. ]:
2143463-35-6

[ Name ]:
MDH1-IN-2

Biological Activity

[Description]:

MDH1-IN-2 (Compound 7c) is a potent and selelctive inhibitor of MDH1 with an IC50 of 2.27 μM. MDH1-IN-2 has the potential for the research of cancer diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Naik R, et al. Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60(20):8631-8646.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H33NO5

[ Molecular Weight ]:
427.53

Related Compounds