Balstilimab

Names

[ CAS No. ]:
2148321-77-9

[ Name ]:
Balstilimab

Biological Activity

[Description]:

Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
Research Areas >> Inflammation/Immunology

[In Vitro]

Balstilimab (AGEN2034) 高亲和力地、选择性地结合 PD-1,并通过阻断 PD-L1 和 PD-L2 与 PD-1 结合从而增强 T 细胞的反应性[1]。

[References]

[1]. Drouin E E, et al. AGEN1884, an IgG1 anti-CTLA-4 antibody, combines effectively with PD-1 blockade in primary human T cell assays and in a non-human primate pharmacodynamic (PD) model. Cancer Research, 2017, 77(13_Supplement): 3654-3654.

Chemical & Physical Properties

No Any Chemical & Physical Properties


Related Compounds