Autotaxin-IN-3

Names

[ Name ]:
Autotaxin-IN-3

Biological Activity

[Description]:

Autotaxin-IN-3 is a Autotaxin(ATX) inhibitor with an IC50 of 2.4 nM, compound 33, sourced from patent WO2018212534A1[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

Research Areas >> Inflammation/Immunology

[Target]

Autotaxin:2.4 nM (IC50)

[In Vitro]

Autotaxin is an enzyme which is responsible for the increase in lysophosphatidic acid in ascites and plasma, and it is a secretory enzyme important for converting lysophosphatidylchloine (LPC) into lysophosphatidic acid (LPA) as a bioactive signaling molecule[1].

[References]

[1]. LEE, Dae Yon, et al. NOVEL COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME. Patent O2018212534A1

Chemical & Physical Properties

[ Density]:
1.482±0.06 g/cm3(Predicted)

[ Boiling Point ]:
807.6±75.0 °C(Predicted)

[ Molecular Formula ]:
C₂₂H₂₁N₉O₂

[ Molecular Weight ]:
443.46

[ Storage condition ]:
2-8°C

Autotaxin-IN-3

Names

Biological Activity

Chemical & Physical Properties

Related Compounds