HIF-1α-IN-3

Names

[ CAS No. ]:
2170715-64-5

[ Name ]:
HIF-1α-IN-3

Biological Activity

[Description]:

HIF-1α-IN-3 (Compound (S)-3f) is a hypoxia-selective HIF-1α inhibitor. HIF-1α-IN-3 shows strong antiestrogenic potency[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase

[Target]

HIF-1α[1]

[References]

[1]. Buravchenko GI, et al. Discovery of derivatives of 6(7)-amino-3-phenylquinoxaline-2-carbonitrile 1,4-dioxides: novel, hypoxia-selective HIF-1α inhibitors with strong antiestrogenic potency. Bioorg Chem. 2020 Nov;104:104324.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₇N₅O₂

[ Molecular Weight ]:
347.37

Related Compounds