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Azido-PEG5-CH2CO2H

Names

[ CAS No. ]:
217180-81-9

[ Name ]:
Azido-PEG5-CH2CO2H

[Synonym ]:
AZIDE-PEG5-CH2COOH

Biological Activity

[Description]:

Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C12H23N3O7

[ Molecular Weight ]:
321.327

[ Exact Mass ]:
321.153595

[ LogP ]:
-1.81

[ Storage condition ]:
2-8°C

Related Compounds