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(S,R,S)-AHPC-CO-C9-acid

Names

[ CAS No. ]:
2172819-78-0

[ Name ]:
(S,R,S)-AHPC-CO-C9-acid

Biological Activity

[Description]:

(S,R,S)-AHPC-CO-C9-acid is an E3 ligase ligand-linker conjugate that can be connected to the ligand for protein to form PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Xu J, et al. AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B. Cancer Discov. 2021 Jul 23.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₃H₄₈N₄O₆S

[ Molecular Weight ]:
628.82

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds