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Gal-C4-Chol

Names

[ CAS No. ]:
219850-70-1

[ Name ]:
Gal-C4-Chol

Biological Activity

[Description]:

Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles[1][2][3].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.  

[2]. Managit C, et al. Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. J Pharm Sci. 2005 Oct;94(10):2266-75.  

[3]. Kawakami S, et al. Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice. Biochim Biophys Acta. 2000 Dec 15;1524(2-3):258-65.  

Chemical & Physical Properties

[ Molecular Formula ]:
C40H69N3O7S

[ Molecular Weight ]:
736.06

Related Compounds