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ACTH (1-13)

Names

[ CAS No. ]:
22006-64-0

[ Name ]:
ACTH (1-13)

[Synonym ]:
adrenocorticotropic hormone fragment*1-13
aMSH peptide
ADRENOCORTICOTROPIC HORMONE (1-13)
SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL
SYSMEHFRWGKPV
ADRENOCORTICOTROPIC HORMONE (1-13),HUMAN
H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-OH
H-SYSMEHFRWGKPV-OH
acth(1-3)
adrenocorticotropic hormone fragment 1-13,human
tridecactide

Biological Activity

[Description]:

ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Peptides
Research Areas >> Inflammation/Immunology

[In Vitro]

Adrenocorticotropic hormone (ACTH) is a tropic hormone produced by the anterior pituitary, regulates cortisol and androgen production and is associated with Addison disease, Cushing syndrome and Cushing disease[2].

[In Vivo]

ACTH (1-13) alone or in combination with met-enkephalin shows potent cytoprotective effects in the model of ethanol induced gastric lesions in rats, and has immunomodulatory effects[1].

[References]

[1]. Mulabegović N, et al. Pharmacodynamic properties of a combination of met-enkephalin and alpha 1-13 adrenocorticotropic hormone. Med Arh. 2008;62(1):41-4.

[2]. Allen MJ, et al. Adrenocorticotropic Hormone (ACTH). StatPearls. 2018.7.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Molecular Formula ]:
C75H106N20O19S

[ Molecular Weight ]:
1623.83000

[ Exact Mass ]:
1622.77000

[ PSA ]:
659.41000

[ LogP ]:
2.71440

[ Index of Refraction ]:
1.684

[ Storage condition ]:
2-8℃

Related Compounds