4-Phenoxybenzoic acid

Names

[ Name ]:
4-Phenoxybenzoic acid

[Synonym ]:
4-Phenoxybenzoic acid
EINECS 218-682-5
MFCD00002539
Benzoic acid,4-phenoxy
Benzoic acid, 4-phenoxy-
p-phenoxybenzoic acid
para-phenoxybenzoic acid
4-Phenoxy-benzoic acid
Benzoic acid, p-phenoxy-
4-Carboxybiphenyl ether
phenoxybenzoic acid
4-Phenoxy-benzoesaeure
Diphenyl ether 4-carboxylic acid
Benzoic acid,p-phenoxy
4-Carboxydiphenyl ether

Biological Activity

[Description]:

4-Phenoxybenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

4-Phenoxybenzoic acid 可以阻断人乳头瘤病毒 (HPV) E2 蛋白的 DNA 结合。它被用作西他沙星的中间体，西他沙星是一种氟喹诺酮类抗生素，有望用于治疗布鲁里溃疡。

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
364.2±25.0 °C at 760 mmHg

[ Melting Point ]:
163-165 °C(lit.)

[ Molecular Formula ]:
C₁₃H₁₀O₃

[ Molecular Weight ]:
214.22

[ Flash Point ]:
141.7±16.7 °C

[ Exact Mass ]:
214.062988

[ PSA ]:
46.53000

[ LogP ]:
3.21

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.608

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Preparation

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Effects of amino acids on the amidation of polyaromatic carboxylic acids by Bacillus cereus.

Biosci. Biotechnol. Biochem. 65(8) , 1761-5, (2001)

The soil bacterium Bacillus cereus Tim-r01 efficiently transformed polyaromatic carboxylic acids (PACA) such as 4-biphenylcarboxylic acid (4-BPCA), 4-biphenylacetic acid, and 4-phenoxybenzoic acid int...

Dioxygenolytic cleavage of aryl ether bonds: 1,2-dihydro-1,2-dihydroxy-4-carboxybenzophenone as evidence for initial 1,2-dioxygenation in 3- and 4-carboxy biphenyl ether degradation.

FEMS Microbiol. Lett. 57(3) , 317-21, (1990)

A bacterial strain, Pseudomonas sp. POB 310, was enriched with 4-carboxy biphenyl ether as sole source of carbon and energy. Resting cells of POB 310 co-oxidize a substrate analogue, 4-carboxybenzophe...

Microarray immunoassay for phenoxybenzoic acid using polymer encapsulated Eu:Gd2O3 nanoparticles as fluorescent labels.

Anal. Chem. 77(21) , 6864-73, (2005)

Currently, detection in microarray bioanalysis is based mainly on the use of organic dyes. To overcome photobleaching and spectral overlaps we applied a new type of fluorophore, crystalline europium-d...