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42-(2-Tetrazolyl)rapamycin

Names

[ CAS No. ]:
221877-56-1

[ Name ]:
42-(2-Tetrazolyl)rapamycin

Biological Activity

[Description]:

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer

[References]

[1]. Karl W. Mollison, et al. Compounds and methods for treatment and prevention of diseases. US 20080171763 A1.

[2]. Ballou LM, et al. Rapamycin and mTOR kinase inhibitors. J Chem Biol. 2008 Nov;1(1-4):27-36.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Molecular Formula ]:
C52H79N5O12

[ Molecular Weight ]:
966.21

Related Compounds