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Cyclic-di-GMP disodium

Names

[ CAS No. ]:
2222132-40-1

[ Name ]:
Cyclic-di-GMP disodium

Biological Activity

[Description]:

Cyclic di-GMP (c-di-GMP) disodium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species[1][2].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Metabolic Disease
Signaling Pathways >> Immunology/Inflammation >> STING

[Target]

STING[1]


[References]

[1]. Wang Z, et, al. STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice. Cancer Immunol Immunother. 2015 Aug;64(8):1057-66.

[2]. Burdette DL, et, al. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 2011 Sep 25;478(7370):515-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H25N10NaO14P2

[ Molecular Weight ]:
714.41

Related Compounds