<Suppliers Price>

DP-b99

Names

[ CAS No. ]:
222315-88-0

[ Name ]:
DP-b99

[Synonym ]:
2,2'-{1,2-Ethanediylbis[oxy-2,1-phenylene({2-[2-(octyloxy)ethoxy]-2-oxoethyl}imino)]}diacetic acid

Biological Activity

[Description]:

DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Kalendarev T, Zupkovitz G, Ioffe V. The unusual gradient elution for reversed phase HPLC of a strong chelator as an active drug substance. J Pharm Biomed Anal. 2001;24(5-6):967-975.

[2]. Diener HC, Schneider D, Lampl Y, Bornstein NM, Kozak A, Rosenberg G. DP-b99, a membrane-activated metal ion chelator, as neuroprotective therapy in ischemic stroke. Stroke. 2008;39(6):1774-1778.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
864.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C42H64N2O12

[ Molecular Weight ]:
788.964

[ Flash Point ]:
476.8±34.3 °C

[ Exact Mass ]:
788.445923

[ LogP ]:
9.53

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.542

Related Compounds