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TPDINPAWYTGRGIRPVGRF-NH2

Names

[ CAS No. ]:
222988-10-5

[ Name ]:
TPDINPAWYTGRGIRPVGRF-NH2

[Synonym ]:
prrp20
thr-pro-asp-ile-asn-pro-ala-trp-tyr-thr-gly-arg-gly-ile-arg-pro-val-gly-arg-phe-nh2
tpdinpawytgrgirpvgrf-nh2

Biological Activity

[Description]:

Prolactin-Releasing Peptide (12-31), rat is a fragment of the prolactin releasing peptide (PrRP). Prolactin-Releasing Peptide (12-31), rat shows high affinity for GPR10 receptors. Prolactin-Releasing Peptide (12-31), stimulates calcium mobilization in CHOK1 cells transfected with the PrRP receptor[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Roland BL, et al. Anatomical distribution of prolactin-releasing peptide and its receptor suggests additional functions in the central nervous system and periphery. Endocrinology. 1999 Dec;140(12):5736-45.  

[2]. Langmead CJ, et al. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Br J Pharmacol. 2000 Oct;131(4):683-8.  

Chemical & Physical Properties

[ Molecular Formula ]:
C104H158N32O26

[ Molecular Weight ]:
2272.57000

[ Exact Mass ]:
2271.20000

[ PSA ]:
938.21000

[ LogP ]:
2.74940

Safety Information

[ WGK Germany ]:
3

Related Compounds