4-Methoxysalicylic acid

Names

[ Name ]:
4-Methoxysalicylic acid

[Synonym ]:
2-hydroxy-4-methoxy-benzoic acid
EINECS 218-801-0
MFCD00002450
4-Methoxysalicylic acid
2-hydroxy-4-methoxybenzoes
4-methoxy-2-hydroxybenzoic acid
2-Hydroxy-p-anisic Acid
2-Hydroxy-4-methoxybenzoic acid
p-methoxysalicylic acid
Benzoic acid, 2-hydroxy-4-methoxy-
2-Hydroxy-4-methoxy-benzoesaeure

Biological Activity

[Description]:

2-Hydroxy-4-methoxybenzoic is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

Natural Products >> Phenols

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
328.7±27.0 °C at 760 mmHg

[ Melting Point ]:
158-159 °C(lit.)

[ Molecular Formula ]:
C₈H₈O₄

[ Molecular Weight ]:
168.147

[ Flash Point ]:
137.9±17.2 °C

[ Exact Mass ]:
168.042252

[ PSA ]:
66.76000

[ LogP ]:
2.24

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.586

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2942000000

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Discovery of protein disulfide isomerase P5 inhibitors that reduce the secretion of MICA from cancer cells.

ChemBioChem. 15(11) , 1599-606, (2014)

In order to regulate the activity of P5, which is a member of the protein disulfide isomerase family, we screened a chemical compound library for P5-specific inhibitors, and identified two candidate c...

Inhibition of Cancer Cell Proliferation and Antiradical Effects of Decoction, Hydroalcoholic Extract, and Principal Constituents of Hemidesmus indicus R. Br.

Phytother Res. 29 , 857-63, (2015)

Indian Sarsaparilla (Hemidesmus indicus R. Br.) is widely used in Indian traditional medicine. In the present work, we explored the effects of decoction, traditional Ayurvedic preparation, and hydroal...

Synthesis, biological evaluation and molecular docking studies of 1,3,4-oxadiazole derivatives as potential immunosuppressive agents.

Bioorg. Med. Chem. 20(10) , 3359-67, (2012)

A series of 1,3,4-oxadiazole derivatives derived from 4-methoxysalicylic acid or 4-methylsalicylic acid (6a-6z) have been first synthesized for their potential immunosuppressive activity. Among them, ...