hGGPPS-IN-2
Names
[ CAS No. ]:
2241547-82-8
[ Name ]:
hGGPPS-IN-2
Biological Activity
[Description]:
hGGPPS-IN-2 (Compound 16g) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-2 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-2 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C20H18FN5O7P2S
[ Molecular Weight ]:
553.40