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BMS-986299

Names

[ CAS No. ]:
2242952-69-6

[ Name ]:
BMS-986299

Biological Activity

[Description]:

BMS-986299 (compound 112) is a first-in-class NLRP3 inflammasome agonist with an EC50 of 1.28 μM. (patent WO2018152396A1).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR)

[Target]

NLRP3:1.28 μM (EC50)

[References]

[1]. Gary Glick, et al. Substituted imidazo-quinolines as nlrp3 modulators. WO2018152396A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₉N₇O

[ Molecular Weight ]:
349.39

Related Compounds