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Thalidomide-O-C6-NH2 hydrochloride

Names

[ CAS No. ]:
2245697-88-3

[ Name ]:
Thalidomide-O-C6-NH2 hydrochloride

Biological Activity

[Description]:

Thalidomide-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Erb MA, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 2017 Mar 9;543(7644):270-274.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H24ClN3O5

[ Molecular Weight ]:
409.86

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds