WS-383 hydrochloride
Names
[ CAS No. ]:
2247544-02-9
[ Name ]:
WS-383 hydrochloride
Biological Activity
[Description]:
WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2[1].
[Related Catalog]:
[Target]
IC50: 11 nM (DCN1-UBC12 interaction)[1]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C18H21Cl2N9S2
[ Molecular Weight ]:
498.46