Efmarodocokin alfa

Names

[ CAS No. ]:
2247840-74-8

[ Name ]:
Efmarodocokin alfa

Biological Activity

[Description]:

Efmarodocokin alfa is a fusion protein of human IL-22 and the IgG4 crystallizable fragment. Efmarodocokin alfa activates IL-22 signaling. Efmarodocokin alfa can be used for the research of severe COVID-19 pneumonia[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Immunology/Inflammation >> Interleukin Related

[Target]

IL-22


[In Vitro]

Efmarodocokin alfa 导致 CRP (C 反应蛋白)显著增加[1]。

[References]

[1]. Waters M, et al. Astegolimab or Efmarodocokin Alfa in Patients With Severe COVID-19 Pneumonia: A Randomized, Phase 2 Trial. Crit Care Med. 2023 Jan 1;51(1):103-116.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds