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P-gp modulator 1

Names

[ CAS No. ]:
2249749-39-9

[ Name ]:
P-gp modulator 1

Biological Activity

[Description]:

P-gp modulator 1 is a high affinity, orally available modulator of P-glycoprotein (Pgp), can reverse the Pgp-mediated multidrug resistance ((MDR)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein

[Target]

P-glycoprotein

[References]

[1]. Ren Q, et al. Design, synthesis, and discovery of ocotillol-type amide derivatives as orally available modulators of P-glycoprotein-mediated multidrug resistance. Eur J Med Chem. 2019 Jan 1;161:118-130.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₁H₇₂N₂O₆

[ Molecular Weight ]:
689.02

Related Compounds