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DBCO-PEG3 acetic-EVCit-PAB

Names

[ CAS No. ]:
2253947-17-8

[ Name ]:
DBCO-PEG3 acetic-EVCit-PAB

Biological Activity

[Description]:

DBCO-PEG4 acetic-EVCit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C54H72N8O13

[ Molecular Weight ]:
1041.20

Related Compounds