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Aminooxy-amido-PEG4-propargyl

Names

[ CAS No. ]:
2253965-03-4

[ Name ]:
Aminooxy-amido-PEG4-propargyl

Biological Activity

[Description]:

Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C13H24N2O6

[ Molecular Weight ]:
304.34

[ Storage condition ]:
-20°C

Related Compounds