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dTAG-47

Names

[ CAS No. ]:
2265886-81-3

[ Name ]:
dTAG-47

Biological Activity

[Description]:

dTAG-47, heterobifunctional dTAG molecule, targets mutant FKBP12 (FKBP12F36V). FKBP12F36V serves as a degradation tag (dTAG) and is fused to a protein of interest. dTAG-47 can be used for the research of basal-like breast cancers (BBC)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC

[References]

[1]. Hai-Tsang Huang, et al. MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife. 2017 Sep 19;6:e26693.

Chemical & Physical Properties

[ Molecular Formula ]:
C59H73N5O14

[ Molecular Weight ]:
1076.24

Related Compounds